Can Hotel Smoke Detectors Detect Vape Can Hotels Detect Vape Smoke Rest Does Vape Set Off Smoke Alarms Do Vapes Set Off Smoke Alarms? A Clear and Simple Vape Smoke Detector Hotel Can Vaping Set Off a Smoke Alarm? Here's What You Need to Know Your guests aren't the only ones checking in. So are their vape pens. With over 13 million regular vapers in the U.S. alone, unauthorized vaping is a major operational risk for hotels. Smoke alarms & e cigarettes in hotel rooms Fire alarm?